Prednisone increases apoptosis in in vitro activated human peripheral blood T lymphocytes
نویسندگان
چکیده
منابع مشابه
Erythropoietin receptor is detectable on peripheral blood lymphocytes and its expression increases in activated T lymphocytes.
We are writing to comment on the article by Lifshitz L et al. published in Haematologica in June 2010: “Macrophages as novel target cells for erythropoietin”. We read the article with great interest but we have to stress that the Authors have passed over our publications concerning immunomodulatory action of recombinant human erythropoietin (rhEPO) from over the last 12 years. Thus, based on ou...
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In this research we have studied the effects of extremely low frequency magnetic field on the peripheral blood lymphocytes chromosomes of human in vitro and rat in vivo. By this means, we used 60 blood samples of 10 men as well as 40 rats. Of 60 human blood samples ,40 samples (in two group of 20) were selected as test groups and placed into the 2 mT and 35 Hz magnetic field. The blood samples,...
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Programmed cell death (apoptosis) is a key mechanism for regulating lymphocyte numbers. Murine lymph node lymphocytes cultured in vitro without added stimuli show significant levels of apoptosis over 24 h, detectable by staining with Annexin V. CD4 and CD8 T lymphocytes from transgenic (Tg) mice expressing single CD45RABC or CD45RO isoforms show increased apoptosis and the extent of apoptosis i...
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A study of the kinetics of RNA and DNA synthesis in PWM-stimulated lymphocytes revealed that RNA synthesis preceded the onset of DNA synthesis by approximately 24 hr and that DNA synthesis and transformation was maximal between 66 to 78 hr. Histochemical and radioautographic studies on PWM stimulated cultures indicated that at 72 hr 50 to 60% of the cell population had been transformed by PWM, ...
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OBJECTIVE To explore the effects of Sterigmatocystin (ST), Deoxynivalenol (DON) and Aflatoxin G1 (AFG1) on apoptosis of human peripheral blood lymphocytes (HPBLs) in vitro and thus to further elucidate the putative roles of these three mycotoxins on human immunosystem. METHODS The effects of ST, DON and AFG1 on apoptosis of HPBLs were studied with cell culture, flow cytometric (FCM) DNA analy...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2007
ISSN: 0009-9104
DOI: 10.1111/j.1365-2249.1996.tb08306.x